Hormones play a major role in the development of the humans, no question or doubt on this. One stands tall among them, the Human Growth Hormone (HGH). This is one of the major hormones of the body which is regulating the physical and cognitive growth of the body. The same goes for animals too but they have a different name. This one hormone is controlling many aspects of the growth functions like physical form, mental state, sex, cognitive functions, etc. People with low HGH may have short stature and are not generally alert. Scientists have created the synthetic HGH in order to cater to the need of people who may need it.
Regulation of HGH
The hormone is secreted by the Pituitary gland but is controlled by the Hypothalamus of the brain. The pituitary release both the hormone and its inhibitors in the blood stream simultaneously. The level of the hormone is balanced based on the quantities of both these and depends on factors like physiological conditions, physical exercises, sleep and free fatty acids. Since the HGH is controlling lot of growth factors, an increased or decreased level affects the various growth activities. Low levels may lead to short stature and growth failure in children and in adults, fat accumulation, lower cell growth and in general less energetic. In these cases, one can administer synthetic human growth hormone to bring back the levels to normal so that general growth is not affected.
Reasons of Low HGH
There are many reasons for the levels to be high or low. A tumor in the pituitary or the hypothalamus is the main reason why the levels are affected. The other reasons include accidents, trauma to the head or any other idiopathic reason. In this case, regulation of the hormone is compulsory as it may affect the overall growth. This is a peptide and as such can be manufactured or extracted from humans. There are about 20 or more commercial versions available in the market.
Benefits of the hormone
In children, the levels in the blood is an average 700mcg and adult around 400mcg. As people age, the levels start to decrease and various growths also start to decrease. The best way to bring the level back to normal is a sound sleep and rest. The hormone is released during sleep cycles. In case of deficiency, injections or tablets can be used. It is found that, more cell generation takes place, energy levels increase, people become more responsive and cognitive functions. In medical use, it can be used for people with renal failure, growth of the intrauterine, short stature, etc. It is also believed to be slow the aging process but there is no clear clinical evidence.
Due to its multifaced benefits, it has been used by people who require it for many reasons. Sports persons and bodybuilders too have been using this for its energy boosting function. However, it is explicitly prohibited in competitive sports. Administering excess levels of synthetic human growth hormone to lead to tumor on the pituitary gland itself, thickening of the bones and jaws, muscle weakness, etc. Hence it is always better to take this drug under medical supervision.